10/31/17 - Yu Matsuzawa publishes in Journal of Experimental Medicine

Congratulations to Yu for his paper coming out online today at Journal of Experimental Medicine!

http://jem.rupress.org/content/early/2017/10/30/jem.20170558

This manuscript shows that autophagy gene ATG16L1, which is associated with inflammatory diseases of the gastrointestinal tract, is essential for preventing necroptotic cell death and loss of Paneth cells in the intestinal epithelium. This work represents a collaboration with the van den Brink Lab at MSKCC where we use both Crohn's disease and graft-versus-host disease models. Thank you to our collaborators and everyone who contributed to this work!

See video explanation of the paper here.